быстрая доставка ~4 недели
Размер
- 100 μg
- 1000 μg
- 500 μg
Rabbit anti-Chicken IL-10 mAb (DET) (RM17836)
- Описание
- Характеристики
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Overview
Product name Rabbit anti-Chicken IL-10 mAb (DET) Catalog No. RM17836 Catagory Elisa Antibody Kit Application ELISA Description Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines including granulocyte-macrophage colony-stimulating factor /GM-CSF, granulocyte colony-stimulating factor/G-CSF, IL-1 alpha, IL-1 beta, IL-6, IL-8 and TNF-alpha. Interferes also with antigen presentation by reducing the expression of MHC-class II and co-stimulatory molecules, thereby inhibiting their ability to induce T cell activation Immunogen Recombinant Purirty Affinity purification Ig Type Rabbit IgG Formulation Supplied as a 0.2um filtered solution in PBS with 0.1%Braveds MB-1, PH 7.8. Application
Recommended
ConcentrationSample ELISA Capture 0.5-4ug/mL Rabbit anti-Chicken IL-10 (CAP)(Cat. No.RM17835) ELISA Detection 0.1-0.4ug/mL Rabbit anti-Chicken IL-10 (DET)(Cat. No.RM17836) Standard 62.5-4000pg/mL Recombinant Chicken IL-10 Protein Rabbit anti-Chicken IL-10 mAb (DET) images
This standard curve is only for demonstration purposes. A standard curve should be generated for eachassay.
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Antibody type Matched antibody pairs Immunogen Recombinant
