быстрая доставка ~4 недели
Размер
- 100 μL
- 20 μL
- 200 μL
- 50 μL
MonoMethyl-YAP1-K342 Rabbit pAb (A18651)
- Описание
- Характеристики
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Overview
Product name MonoMethyl-YAP1-K342 Rabbit pAb Catalog No. A18651 Host species Rabbit Purification method Affinity purification Isotype IgG Background
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.Immunogen information
Immunogen A synthetic monomethylated peptide around K342 of human YAP1 (NP_001123617.1). Sequence SPKCQ Gene ID Swiss Prot Synonyms YAP; YKI; COB1; YAP2; YAP-1; YAP65 Calculated MW 54kDa Observed MW 70kDa Applications
Reactivity Human, Mouse, Rat Tested applications WB Recommended dilution - WB 1:500 - 1:2000
Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.Key application Western blotting Positive samples Mouse kidney, Rat liver Cellular location Cytoplasm, Nucleus 
Western blot analysis of extracts of various cell lines, using MonoMethyl-YAP1-K342 Rabbit pAb (A18651) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit (RM00021).
Exposure time: 3min. -
Key applications Western blotting Host species Кролик Antibody type Primary Antibodies Reactivity Человек, Мышь, Крыса Immunogen A synthetic monomethylated peptide around K342 of human YAP1 (NP_001123617.1). Isotype IgG