быстрая доставка ~4 недели
Размер
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ABflo® 488 Rabbit anti-Human CD201/EPCR mAb (A24226)
- Описание
- Характеристики
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Overview
Product name ABflo® 488 Rabbit anti-Human CD201/EPCR mAb Catalog No. A24226 Host species Rabbit Purification method Affinity purification Isotype IgG CloneNo. ARC60942-ABflo488 Background
The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer.Immunogen information
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 18-210 of human CD201/EPCR (NP_006395.2). Sequence QDASDGLQRLHMLQISYFRDPYHVWYQGNASLGGHLTHVLEGPDTNTTIIQLQPLQEPESWARTQSGLQSYLLQFHGLVRLVHQERTLAFPLTIRCFLGCELPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNAYNRTRYELREFLEDTCVQYVQKHISAENTKGSQTSRSYTS Gene ID Swiss Prot Synonyms PROCR; CCCA; CCD41; EPCR; protein C receptor Calculated MW 26kDa Observed MW Applications
Reactivity Human Tested applications FC Recommended dilution - FC 5 μl per 10^6 cells in 100 μl volume
Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.03% proclin300, 0.2% BSA, 50% glycerol, pH7.3.Key application Flow Cytometry Positive samples Cellular location Membrane, Single-pass type I membrane protein 
Flow cytometry: 1X10^6 Jurkat cells(low Expression, left) and A549 (right) were surface-stained with ABflo® 488 Rabbit anti-Human CD201/EPCR mAb(A24226, 5 μl/Test, orange line) or ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, blue line).Non-fluorescently stained cells were used as blank control (red line).
Flow cytometry:1X10^6 A549 cells were surface-stained ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, left) or ABflo® 488 Rabbit anti-Human CD201/EPCR mAb(A24226, 5 μl/Test, right).
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Key applications Flow Cytometry Host species Кролик Antibody type Primary Antibodies Reactivity Человек Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 18-210 of human CD201/EPCR (NP_006395.2). Isotype IgG