быстрая доставка ~4 недели
Размер
- 100 μL
- 20 μL
- 200 μL
- 50 μL
2'-O-Methylguanosine(Gm) Rabbit mAb (A20696)
- Описание
- Характеристики
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Overview
Product name 2'-O-Methylguanosine(Gm) Rabbit mAb Catalog No. A20696 Host species Rabbit Purification method Affinity purification Isotype IgG CloneNo. ARC50772 Background
RNA methylation plays a significant regulatory role in various of physiological activities and it has gradually become a hotspot of epigenetics in the past decade. 2'-O-methyladenosine (Am), 2'-O-methylguanosine (Gm), 2'-O-methylcytidine (Cm), 2'-O-methyluridine (Um), N 6-methyladenosine (m6A), N 1-methylguanosine (m1G), 5-methylcytidine (m5C), and 5-methyluridine (m5U) are representative 2'-O-methylation and base-methylation modified epigenetic marks of RNA. 2'-O-methyltransferase is a modified nucleoside that is produced in tRNAs by the action of tRNA guanosine-2'-O-methyltransferase, using S-adenosyl-L-methionine as a substrate. Through its interaction with other modified nucleosides, 2'-O-methylguanosine is thought to stabilize the structure of the tRNA.Immunogen information
Immunogen Gm Sequence Gm conjugated to KLH Gene ID Swiss Prot Synonyms 2'-O-Methylguanosine; Gm Calculated MW Observed MW Refer to figures Applications
Reactivity Species independent Tested applications DB Recommended dilution - DB 1:500 - 1:2000
Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.Key application Positive samples Cellular location 
The 2'-O-methylguanosine(Gm) Rabbit mAb (A20696) are tested in Dot Blot against 2'-O-methylguanosine and unmodified guanosine.2'-O-methylguanosine：Biotin-5'GCATAATGACTACT(Gm)3'unmodified guanosine：Biotin-5'GCATAATGACTACTG3'
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Host species Кролик Antibody type Primary Antibodies Reactivity Независимый от вида Immunogen Gm Isotype IgG