Product Information
| Description | Fatty Acid Synthase mouse monoclonal |
| Protein full name | Fatty acid synthase |
| Synonyms | FASN, fatty acid synthase, Fasn, A630082H08Rik, FAS, OA-519, SDR27X1, Fatty acid synthase |
| Immunogen | Recombinant protein corresponding to Mouse Fatty acid synthase |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location | Cytoplasm |
| Predicted MW. | 273 kDa |
| Observed MW. | 273 kDa |
| Uniprot ID | P19096 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| IHC | Mouse | 1: 1000-1: 2000 | kidney |
| WB | Mouse | 1: 500-1: 1000 | brain |
Background
Fatty acid synthase is a multi-enzyme protein that catalyzes fatty acid synthesis. It is not a single enzyme but a whole enzymatic system composed of two identical 272 kDa multifunctional polypeptides, in which substrates are handed from one functional domain to the next. Its main function is to catalyze the synthesis of palmitate (C16:0, a long-chain saturated fatty acid) from acetyl-CoA and malonyl-CoA, in the presence of NADPH.
Images
| Western blot analysis of Fatty Acid Synthase (GB12547) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin-embedded mouse kidney using Fatty Acid Synthase (GB12547) at dilution of 1: 2000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
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