Product Information
Description | Fibronectin mouse monoclonal |
Protein full name | Fibronectin |
Synonyms | FN,Fn1, CIG, FINC, Migration stimulating factor, MSF, GFND |
Immunogen | Human plasma-derived Fibronectin protein |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
IHC | Human | 1: 200-1: 400 | cholangiocarcinoma, esophageal carcinoma, gastric carcinoma |
Background
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.
Images
| Immunohistochemistry analysis of paraffin-embedded human cholangiocarcinoma using Fibronectin (GB12091) at dilution of 1: 400. Protease K was used to repair antigen for 30min at 37 ℃ temperature. |
| Immunohistochemistry analysis of paraffin-embedded human esophageal carcinoma using Fibronectin (GB12091) at dilution of 1: 400. Protease K was used to repair antigen for 30min at 37 ℃ temperature. |
| Immunohistochemistry analysis of paraffin-embedded human gastric carcinoma using Fibronectin (GB12091) at dilution of 1: 400. Protease K was used to repair antigen for 30min at 37 ℃ temperature. |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
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