Product Information
Description | Annexin-6 rabbit polyclonal |
Protein full name | Annexin A6 |
Synonyms | 67 kDa calelectrin, Annexin VI, Annexin-6, Calphobindin-II, CPB-II, Chromobindin-20, Lipocortin VI, Protein III, p68, p70,Anxa6, Anx6, Annexin-6 |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Annexin-6 |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 76 kDa |
Observed MW. | 76 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | liver, lung, kidney |
Background
ANXA6, also called CBP68 or 67 kDa calelectrin, belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kBDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.
Images
| Western blot analysis of Annexin-6 (GB11949) at dilution of 1: 500 Lane 1: Mouse liver tissue lysate Lane 2: Mouse lung tissue lysate Lane 3: Mouse kidney tissue lysate Lane 4: Rat liver tissue lysate Lane 5: Rat lung tissue lysate Lane 6: Rat kidney tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
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