Product Information
Description | CD62L rabbit polyclonal |
Protein full name | L-selectin |
Synonyms | SELL, CD62L, LAM1, LECAM1, LEU8, LNHR, LSEL, LYAM1, PLNHR, TQ1, selectin L |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse CD62L |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 42 kDa |
Observed MW. | 42 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | spleen, splenitis, thymus |
Background
L-selectin, also known as CD62L, is a cell adhesion molecule found on lymphocytes and the preimplantation embryo. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17. CD62L contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. CD62L is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites.
Images
| Western blot analysis of CD62L (GB11632) at dilution of 1: 1000 Lane 1: A549 cell lysate Lane 2: Jurkat cell lysate Lane 3: HepG2 cell lysate Lane 4: Mouse spleen tissue lysate Lane 5: Mouse splenitis tissue lysate Lane 6: Mouse thymus tissue lysate Lane 7: Rat spleen tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
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