Product Information
Description | Aurora A rabbit polyclonal |
Protein full name | Aurora kinase A |
Synonyms | AURKA, AIK, ARK1, AURA, Aurora A, BTAK, PPP1R47, STK15, STK6, STK7, aurora kinase A |
Immunogen | Recombinant protein corresponding to Mouse Aurora A |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 45 kDa |
Observed MW. | 47 kDa |
Uniprot ID |
Applications
applications | species | dilution | positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | gastric carcinoma, liver cancer, ovary, testis |
Background
Aurora kinase A also known as serine/threonine-protein kinase 6, is a member of a family of mitotic serine/threonine kinases. It is implicated with important processes during mitosis and meiosis whose proper function is integral for healthy cell proliferation. Aurora A is activated by one or more phosphorylations and its activity peaks during the G2 phase to M phase transition in the cell cycle.
Images
| Western blot analysis of Aurora A (GB11577) at dilution of 1: 800 Lane 1: Human gastric carcinoma tissue lysate Lane 2: Human liver cancer tissue lysate Lane 3: Mouse ovary tissue lysate Lane 4: Mouse testis tissue lysate Lane 5: Rat ovary tissue lysate Lane 6: Rat testis tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles |
| Storage Buffer | PBS with 0.02%sodium azide, 100 μg/ml BSA and 50% glycerol. |
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