Product Information
Description | CCR7 rabbit polyclonal |
Protein full name | C-C chemokine receptor type 7 |
Synonyms | BLR2, CC-CKR-7, CCR-7, CD197, CDw197, CMKBR7, EBI1, C-C motif chemokine receptor 7 |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse CCR7 |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 43 kDa |
Observed MW. | 48 kDa |
Uniprot ID |
Applications
applications | species | dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | thymus, spleen |
Background
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor.
Images
| Western blot analysis of CCR7 (GB11503) at dilution of 1:800. Lane 1:Jukat cell lysate Lane 2:THP-1 cell lysate Lane 3:Raw264.7 cell lysate Lane 4:Mouse Inflammatory spleen tissue lysate Lane 5:Mouse Inflammatory liver tissue lysate Lane 6:Mouse thymus tissue lysate Lane 7:Rat Inflammatory spleen tissue lysate Lane 8:Rat Inflammatory liver tissue lysate Lane 9:Rat thymus tissue lysate |
| Western blot analysis of preincubated with the control peptide antigen (left) and CCR7 (GB11503) at dilution of 1:800(right). Lane 1:Jurkat cell lysate Lane 2:THP-1 cell lysate Lane 3:Mouse thymus tissue lysate Lane 4:Rat thymus tissue lysate |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
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