Product Information
Description | Mineralocorticoid receptor rabbit polyclonal |
Protein full name | Mineralocorticoid receptor |
Synonyms | NR3C2, MCR, MLR, MR, NR3C2VIT, nuclear receptor subfamily 3 group C member 2 |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Mineralocorticoid receptor |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
IHC | Human, Mouse, Rat | 1: 500-1: 1000 | stomach, brain, heart, liver, kidney |
IF | Human, Mouse, Rat | 1: 500-1: 1000 | stomach, brain, heart, liver, kidney |
Background
Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
Images
| Immunohistochemistry analysis of paraffin-embedded human stomach using Mineralocorticoid receptor (GB11379-1) at dilution of 1: 750 |
| Immunohistochemistry analysis of paraffin-embedded mouse kidney using Mineralocorticoid receptor (GB11379-1) at dilution of 1: 750 |
| Immunohistochemistry analysis of paraffin-embedded rat heart using Mineralocorticoid receptor (GB11379-1) at dilution of 1: 750 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
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