Product Information
Description | Lamr1 rabbit polyclonal |
Protein full name | 40S ribosomal protein SA |
Synonyms | 37 kDa laminin receptor precursor, 37LRP, 37 kDa oncofetal antigen, 37/67 kDa laminin receptor, LRP/LR, 67LR, Laminin receptor 1, LamR, LBP/p40,Rpsa, Lamr1, P40-8 |
Immunogen | Recombinant protein corresponding to Mouse Lamr1 |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 33 kDa |
Observed MW. | 40 kDa |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | brain, liver |
Background
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function.It is overexpressed in various cancer cell lines, and the the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype.
Images
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Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE: This product is intended for research only.
