Артикул
GB111330
быстрая доставка ~4 недели
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Anti -5 Lipoxygenase/5-LO Rabbit pAb
- Описание
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Product Information
Description 5 Lipoxygenase rabbit polyclonal
Protein full name Arachidonate 5-lipoxygenase Synonyms
5-LO, 5-lipoxygenase, Alox5, 5-LOX, 5LPG, LOG5, Arachidonic acid 5 lipoxygenase, Leukotriene A4 synthase
Immunogen Recombinant protein corresponding to Mouse 5 Lipoxygenase
Isotype IgG Purity Affinity purification Subcellular location Cytoplasm, Nucleus Predicted MW.
78 kDa
Observed MW.
78 kDa
Uniprot ID Applications
Applications
Species
Dilution
Positive Tissue
WB
Human, Mouse, Rat
1: 500-1: 800
thymus, brain IHC
Human, Mouse, Rat
1: 2000-1: 4000
prostate cancer, breast cancer, stomach cancer, lung, bone, colon,
small intestineIF
Human, Mouse, Rat
1: 2000-1: 4000
lung, colon, stomach Background
ALOX5(arachidonate 5-lipoxygenase) is also named as LOG5, 5-LO and belongs to the lipoxygenase family. It catalyzes the first step in leukotriene biosynthesis, and plays a role in inflammatory processes. It is a 78 kDa iron-containing enzyme that translocates from the cytosol to associate with FLAP, and converts arachidonate in two steps into the unstable intermediate LTA4. It is essential for cysteinyl-leukotriene (cys-LT) production, critical mediators in asthma.
Images
Western blot analysis of ALOX5 (GB111330) at dilution of 1: 500
Lane 1: THP-1 cell lysate
Lane 2: K562 cell lysate
Lane 3: U266 cell lysate
Lane 4: 8226 cell lysate
Lane 5: Mouse thymus tissue lysate
Lane 6: Mouse brain tissue lysate
Lane 7: Rat brain tissue lysate
Immunohistochemistry analysis of paraffin-embedded human prostate cancer using ALOX5 (GB111330) at dilution of 1: 2000 
Immunohistochemistry analysis of paraffin-embedded human breast cancer using
ALOX5 (GB111330) at dilution of 1: 2000
Immunohistochemistry analysis of paraffin-embedded human stomach cancer using ALOX5 (GB111330) at dilution of 1: 2000 
Immunohistochemistry analysis of paraffin-embedded human lung using
ALOX5 (GB111330) at dilution of 1: 2000
Immunohistochemistry analysis of paraffin-embedded mouse lung using
ALOX5 (GB111330) at dilution of 1: 2000
Immunohistochemistry analysis of paraffin-embedded rat lung using
ALOX5 (GB111330) at dilution of 1: 2000
Immunohistochemistry analysis of paraffin-embedded mouse bone using
ALOX5 (GB111330) at dilution of 1: 2000
Immunohistochemistry analysis of paraffin-embedded rat bone using
ALOX5 (GB111330) at dilution of 1: 2000
Immunohistochemistry analysis of paraffin-embedded rat colon using
ALOX5 (GB111330) at dilution of 1: 2000
Immunohistochemistry analysis of paraffin-embedded rat small intestine using
ALOX5 (GB111330) at dilution of 1: 2000
Immunofluorescent analysis of paraformaldehyde-fixed human lung using
ALOX5 (GB111330) at dilution of 1: 2000
Immunofluorescent analysis of paraformaldehyde-fixed mouse lung using
ALOX5 (GB111330) at dilution of 1: 2000
Immunofluorescent analysis of paraformaldehyde-fixed rat colon using
ALOX5 (GB111330) at dilution of 1: 2000
Immunofluorescent analysis of paraformaldehyde-fixed rat stomach using
ALOX5 (GB111330) at dilution of 1: 2000Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
