Product Information
Description | IL-6 rabbit polyclonal |
Protein full name | Interleukin-6 |
Synonyms | IL6, BSF2, HGF, HSF, IFNB2, IL-6, BSF-2, CDF, IFN-beta-2, interleukin 6 |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse IL-6 |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
IHC,IF | Mouse,Rat | 1: 500-1: 800 | inflammatory lung, kidney |
Background
Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.
Images
| Immunohistochemistry analysis of paraffin-embedded rat kidney using IL-6 (GB11117) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin-embedded mouse inflammatory lung using IL-6 (GB11117) at dilution of 1: 800 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE: This product is intended for research only.
