Product Information
Description | Aggrecan rabbit polyclonal |
Protein full name | Aggrecan core protein |
Synonyms | ACAN, AGC1, AGCAN, CSPG1, CSPGCP, MSK16, SEDK, Aggrecan |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Aggrecan |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | |
Uniprot ID |
Applications
applications | species | dilution | Positive tissue |
IHC | Mouse, Rat | 1: 500-1: 1000 | bone |
IF | Mouse, Rat | 1: 500-1: 1000 | bone |
Background
Aggrecan (ACAN), also known as cartilage-specific proteoglycan core protein (CSPCP) or chondroitin sulfate proteoglycan 1, is a protein that in humans is encoded by the ACAN gene. This gene is a member of the lectican (chondroitin sulfate proteoglycan) family. This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.
Images
| Immunohistochemistry analysis of paraffin-embedded mouse bone using Aggrecan (GB11373) at dilution of 1:500. |
| Immunohistochemistry analysis of paraffin-embedded rat bone using Aggrecan (GB11373) at dilution of 1:500. |
| Immunohistochemistry analysis of paraffin-embedded rat bone using Aggrecan (GB11373) at dilution of 1:500. |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
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