- Описание
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Product Information
Description
Aldolase rabbit polyclonal antibody
Protein full name
Fructose-bisphosphate aldolase A
Synonyms
Aldolase 1, Muscle-type aldolase, Aldoa, Aldo1, Aldolase A, Fructose 1 6 bisphosphate triosephosphate lyase, GSD12, Lung cancer antigen NY LU 1
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Aldolase
Isotype
IgG
Purity
Affinity purification
Predicted MW.
39 kDa
Observed MW.
39 kDa
Uniprot ID
P05064, P05065
Applications
Applications
Species
Dilution
Positive Tissue
WB
Mouse, Rat
1: 500-1: 1000
skeletal muscle, brain, heart
Background
Aldolase A (fructose bisphosphate aldolase) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3 phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Research studies suggest that Aldolase A is upregulated in various cancers, including human lung squamous and renal cell carcinomas. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants which encode the same protein.
Images

Western blot analysis of ALDA (GB11956) at dilution of 1: 500
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).







