- Описание
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Product Information
Description
AACT rabbit polyclonalantibody
Protein full name
Alpha-1-antichymotrypsin
Synonyms
ACT, Cell growth-inhibiting gene 24/25 protein, Serpin A3,Alpha-1-antichymotrypsin His-Pro-less,SERPINA3, AACT
Immunogen
Recombinant protein corresponding to Human AACT
Isotype
IgG
Purity
Affinity purification
Predicted MW.
48 kDa
Observed MW.
48 kDa
Uniprot ID
Applications
Applications
Species
Dilution
Positive Tissue
WB
Human, Mouse, Rat
1: 500-1: 1000
spleen
Background
The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. It is a plasma alpha globulin glycoprotein which increases in the blood during the inflammatory process. SerpinA3, is also an inhibitor of neutrophil cathepsin G, mast cell chymases and pancreatic chymotrypsin. SerpinA3 is produced primarily in the liver, and is identified as an acute-phase inflammatory protein. SerpinA3 deficiency has been associated with liver disease. SerpinA3 has also been implicated in the pathology of a number of devastating human diseases including chronic obstructive pulmonary disease (COPD), Parkinson’s disease (PD), Alzheimer’s disease (AD), Stroke, Cystic Fibrosis, Cerebral Haemorrhage and Multiple System Atrophy.
Images

Western blot analysis of SERPINA3 (GB11871) at dilution of 1: 500
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).







