- Описание
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Product Information
Description
ADRA1B rabbit polyclonal antibody
Protein full name
Alpha-1B adrenergic receptor
Synonyms
ADRA1, ADRA1B, Alpha-1B adrenoceptor, Alpha-1B adrenoreceptor, ALPHA1BAR
Immunogen
KLH conjugated Synthetic peptide
corresponding to Mouse ADRA1B
Isotype
IgG
Purity
Affinity purification
Subcellular location
Uniprot ID
Applications
Applications
Species
Dilution
Positive Sample
IHC/IF
Human, Mouse, Rat
1:400-1:1200
colon cancer, ovarian cancer, kidney, spleen, testis, brain
Background
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
Images

Immunohistochemistry analysis of paraffin-embedded human colon cancer using ADRA1B (GB113857) at dilution of 1: 1200 
Immunohistochemistry analysis of paraffin-embedded human ovarian cancerusing ADRA1B (GB113857) at dilution of 1: 1200 
Immunohistochemistry analysis of paraffin-embedded mouse kidney using ADRA1B (GB113857) at dilution of 1: 1200

Immunohistochemistry analysis of paraffin-embedded mouse spleen using ADRA1B (GB113857) at dilution of 1: 1200

Immunohistochemistry analysis of paraffin-embedded rat testis using ADRA1B (GB113857) at dilution of 1: 1200

Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using ADRA1B (GB113857) at dilution of 1: 1200

Immunofluorescent analysis of paraformaldehyde-fixed rat kidney using ADRA1B (GB113857) at dilution of 1: 1200
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).













