Артикул
GB113832
быстрая доставка ~4 недели
Наши менеджеры обязательно свяжутся с вами и уточнят условия заказа
Anti -Aconitase 2 Rabbit pAb
- Описание
-
Product Information
Description
Aconitase 2 rabbit polyclonal antibody
Protein full name
Aconitate hydratase, mitochondrial
Synonyms
ACO2, Aconitase, aconitase 2, ACONM, Citrate hydro lyase
Immunogen
KLH conjugated Synthetic peptide
corresponding to Mouse Aconitase 2
Isotype
IgG
Purity
Affinity purification
Subcellular location
Mitochondrion
Predicted MW.
85 kDa
Observed MW.
95kDa
Uniprot ID
Applications
Applications
Species
Dilution
Positive Sample
WB
Human, Mouse, Rat
1:1000-1:3000
kidney, brain, lung
IHC/IF
Mouse, Rat
1:300-1:1000
brain, heart, kidney, testis, thyroid gland
Background
ACO2(aconitate hydratase, mitochondrial) is also named as citrate hydro-lyase and belongs to the aconitase/IPM isomerase family. It plays a key function in cellular energy production, and loss of its activity has a major impact on cellular and organismal survival. Western blot shows two bands of 83 kDa and 40 kDa. The 40 kDa fragment decreases with age and oxidative stress, whereas other fragmentation products with molecular weights between 40 and 83 kDa increased with age and MnSOD(mitochondrial manganese superoxide dismutase) deficiency. Defects in ACO2 are the cause of infantile cerebellar-retinal degeneration (ICRD).
Images
Western blot analysis of ACO2 (GB113832) at dilution of 1: 3000
Immunohistochemistry analysis of paraffin-embedded rat brain using ACO2 (GB113832) at dilution of 1: 1000
Immunofluorescent analysis of paraformaldehyde-fixed rat heart using ACO2 (GB113832) at dilution of 1: 1000
Immunofluorescent analysis of paraformaldehyde-fixed rat kidney using ACO2 (GB113832) at dilution of 1: 1000
Immunofluorescent analysis of paraformaldehyde-fixed mouse kidney using ACO2 (GB113832) at dilution of 1: 1000
Immunofluorescent analysis of paraformaldehyde-fixed rat heart using ACO2 (GB113832) at dilution of 1: 1000
Immunofluorescent analysis of paraformaldehyde-fixed rat testis using ACO2 (GB113832) at dilution of 1: 1000
Immunofluorescent analysis of paraformaldehyde-fixed rat thyroid gland using ACO2 (GB113832) at dilution of 1: 1000 Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.