- Описание
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Product Information
Description
ACSL3rabbit polyclonal
Protein full name
Long-chain-fatty-acid--CoA ligase 3
Synonyms
Long-chain acyl-CoA synthetase 3, Arachidonate--CoA ligase, ACS3, ACSL3, FACL3, LACS 3, LACS3, PRO2194
Immunogen
KLH conjugated Synthetic peptide
corresponding to Mouse ACSL3
Isotype
IgG
Purity
Affinity purification
Predicted MW.
80 kDa
Observed MW.
80kDa
Uniprot ID
Applications
Applications
Species
Dilution
Positive Tissue
WB
Human
1:300-1:600
HepG2, MCF-7, THP-1, 293T, Jurkat, A-431
Background
ACSL3, also named as ACS3, FACL3 and LACS3, belongs to the ATP-dependent AMP-binding enzyme family. Acyl-CoA synthetases (ACSL) activate long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL3 mediates hepatic lipogenesis. Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates. Has mainly an anabolic role in energy metabolism. Required for the incorporation of fatty acids into phosphatidylcholine, the major phospholipid located on the surface of VLDL (very low density lipoproteins). The antibody is specific to ACSL3.
Images

Western blot analysis of ACSL3 (GB113698)
at dilution of 1: 600
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).







