- Описание
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Product Information
Description
Insulin Receptor betarabbit polyclonal
Protein full name
Insulin receptor
Synonyms
CD220, HHF5, INSR, IR, Insulin receptor subunit beta
Immunogen
KLH conjugated Synthetic peptide corresponding to mouse Insulin Receptor beta
Isotype
IgG
Purity
Affinity purification
Predicted MW.
156 kDa
Observed MW.
95/220 kDa
Uniprot ID
Applications
Applications
Species
Dilution
Positive Tissue
WB
Mouse, Rat
1:500-1:1000
liver, fat, skeletal muscle
Background
The biological effects of INS are mediated by a membrane spanning cell surface receptor that has been shown to consist of disulfide-linked 135-kDa and 95-kDa alpha- and beta-subunits that are cleaved products of a common precursor. Binding of INS to the receptor extracellular domain results in intracellular activation of a tyrosine-specific kinase activity and the generation of signals that determine the cellular response . This antibody raised against 980-1382aa of human INS receptor can recognize full-length INS receptor precursor and INS receptor beta subunit.
Images

Western blot analysis of INSR (GB113501)
at dilution of 1: 1000
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).







