Артикул
GB112996
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Anti -AKR1C1/AKR1C2 Rabbit pAb
- Описание
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Product Information
Description
AKR1C1/AKR1C2rabbit polyclonal
Protein full name
Aldo-keto reductase family 1 member C2
Synonyms
3-alpha-HSD3, Chlordecone reductase homolog HAKRD, Dihydrodiol dehydrogenase 2, DD-2, DD2, DD/BABP,AKR1C2, DDH2, Type III 3-alpha-hydroxysteroid dehydrogenase, MBAB, HBAB
Immunogen
KLH conjugated Synthetic peptide
corresponding to Human AKR1C1/AKR1C2
Isotype
IgG
Purity
Affinity purification
Subcellular location
Predicted MW.
37kDa
Observed MW.
37kDa
Uniprot ID
Applications
Applications
Species
Dilution
Positive Tissue
WB Human
1:500-1:1000
HeLa, HepG2, A549
Background
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.
Images
Western blot analysis of AKR1C1/AKR1C2 (GB112996) at dilution of 1: 1000
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.