Артикул
GB112422
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Anti -AGXT2L2 Rabbit pAb
- Описание
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Product Information
Description
AGXT2L2 rabbit polyclonal antibody
Protein full name
5-phosphohydroxy-L-lysine phospho-lyase
Synonyms
lanine--glyoxylate aminotransferase 2-like 2, Phykpl, Agxt2l2
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse AGXT2L2
Isotype
IgG
Purity
Affinity purification
Predicted MW.
52 kDa
Observed MW.
55 kDa
Uniprot ID
Q8IUZ5, Q8R1K4
Applications
Applications
Species
Dilution
Positive Tissue
WB
Human, Mouse, Rat
1:1000-1:2000
brain, spinal cord
Background
AGXT2 protects from asymmetric dimethylarginine (ADMA)-induced inhibition in nitric oxide (NO) production. Elevated blood concentrations of ADMA, a methyl derivate of the amino acid arginine and an endogenous inhibitor of nitric oxide (NO) synthase, is produced by the physiological degradation of methylated proteins and is found in association with diabetes, hypertension, congestive heart failure and atherosclerosis. AGXT2L2 (alanine-glyoxylate aminotransferase 2-like 2) is a 450 amino acid pyridoxal phosphate that exists as a homotetramer. Belonging to the class-III pyridoxal-phosphate-dependent aminotransferase family, AGXT2L2 localizes to the mitochondria and exists as three alternatively spliced isoforms.
Images
Western blot analysis of AGXT2L2 (GB112422) at dilution of 1: 1000
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.