- Описание
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Product Information
Description
AC5 rabbit polyclonal antibody
Protein full name
Adenylate cyclase type 5
Synonyms
ATP pyrophosphate-lyase 5, Adenylate cyclase type V, Adenylyl cyclase 5, Adcy5, AC5
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse AC5
Isotype
IgG
Purity
Affinity purification
Subcellular location
Cell membrane
Uniprot ID
O95622
Applications
Applications
Species
Dilution
Positive Sample
IHC/IF
Human
1: 50-1: 200
kidney
Background
This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene.
Images

Immunohistochemistry of paraffin embedded human kidney using ADCY5-6 (GB112418) at dilution of 1:60 (400x lens)
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).







