- Описание
-
Product Information
Description
5HT6 Receptor rabbit polyclonal antibody
Protein full name
5-hydroxytryptamine receptor 6
Synonyms
5-HT-6, 5-HT6, Serotonin receptor 6, Htr6
Immunogen
Recombinant protein corresponding to Mouse 5HT6 Receptor
Isotype
IgG
Purity
Affinity purification
Subcellular location
Cell membrane
Predicted MW.
47 kDa
Observed MW.
47 kDa
Uniprot ID
P50406, Q9R1C8, P31388
Applications
Applications
Species
Dilution
Positive Sample
WB
Human, Mouse, Rat
1: 500-1: 1000
brain, cerebral cortex
IHC/IF
Mouse, Rat
1: 600-1: 1200
corpus striatum, prefrontal lobe
Background
This gene encodes a protein that belongs to the seven-transmembrane G protein-coupled receptor family of proteins. The encoded protein couples with the Gs alpha subunit and stimulates adenylate cyclase to activate the cyclic AMP-dependent signaling pathway. This receptor is thought to regulate cholinergic neuronal transmission in the brain. Several antidepressants and antipsychotic drugs have a high affinity for this receptor.
Images

Western blot analysis of 5HT6 (GB112416) at dilution of 1: 500 
Immunofluorescence of paraffin embedded mouse prefrontal lobe using 5HT6 (GB112416) at dilution of 1: 600 (400x lens) 
Immunofluorescence of paraffin embedded rat corpus striatum using 5HT6 (GB112416) at dilution of 1: 600 (250x lens)
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).










