Артикул
GB112322
быстрая доставка ~4 недели
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Anti -A4GNT Rabbit pAb
- Описание
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Product Information
Description
A4GNT rabbit polyclonal antibody
Protein full name
Alpha-1,4-N-acetylglucosaminyltransferase
Synonyms
Alpha4GnT, A4gnt, Alpha 1 4 N acetylglucosaminyltransferase, 4-N-acetylglucosaminyltransferase
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse A4GNT
Isotype
IgG
Purity
Affinity purification
Predicted MW.
39 kDa
Observed MW.
39 kDa
Uniprot ID
Q9UNA3, Q14BT6
Applications
Applications
Species
Dilution
Positive Sample
WB
Human, Mouse, Rat
1: 500-1: 1000
pancreas, kidney, stomach
Background
Alpha 1,4-N-acetylflucosaminyltransferase (Alpha4Gn-T) mediates the biosynthesis of mucin type glycoprotein (O-glycan). Alpha4Gn-T acts as the key enzyme for the formation of the unique glycan GlcNAcalpha1-4Galbeta1-R, and most efficiently transfers N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Alpha4Gn-T is a single-pass type II membrane protein associated with the Golgi apparatus and contains the conserved DXD motif involved in catalytic activity. It is expressed in stomach and pancreas, as well as in gastric cancer cells. Alpha4Gn-T is not expressed in peripheral blood cells, making it a useful biomarker for pancreatic cancer.
Images
Western blot analysis of A4gnt (GB112322) at dilution of 1: 500
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.