Артикул
GB111881
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Anti -ALDH2 Rabbit pAb
- Описание
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Product Information
Description
ALDH2 rabbit polyclonal antibody
Protein full name
Aldehyde dehydrogenase, mitochondrial
Synonyms
AHD-M1, ALDH class 2, ALDH-E2, ALDHI, Aldh2, Ahd-1,Ahd1, MS767, Liver mitochondrial ALDH
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse ALDH2
Isotype
IgG
Purity
Affinity purification
Predicted MW.
57 kDa
Observed MW.
57 kDa
Uniprot ID
P05091, P47738, P11884
Applications
Applications
Species
Dilution
Positive Tissue
WB
Human, Mouse, Rat
1: 500-1: 1000
liver
Background
Acetaldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. It mediates NADP+-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde; lipid peroxidation; and metabolism of corticosteroids, biogenic amines and neurotransmitters. Genetic variation in ALDH2 is responsible for individual differences in responses to drinking alcohol. Thus, the absence of this enzyme is linked to alcohol intolerance and a reduced risk for alcoholism-related liver disease.
Images
Western blot analysis of ALDH2 (GB111881) at dilution of 1: 500
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.