Артикул
GB111166
быстрая доставка ~4 недели
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Anti -14-3-3 Tau Rabbit pAb
- Описание
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Product Information
Description
14-3-3 Tau rabbit polyclonal antibody
Protein full name
14-3-3 protein theta
Synonyms
14-3-3 protein tau, Ywhaq
Immunogen
Recombinant protein corresponding to Mouse 14-3-3 Tau
Isotype
IgG
Purity
Affinity purification
Predicted MW.
28 kDa
Observed MW.
28 kDa
Uniprot ID
P27348, P68254, P68255
Applications
Applications
Species
Dilution
Positive Tissue
WB
Human, Mouse, Rat
1: 500-1: 1000
brain, lung, thymus
Background
The 14-3-3 family of proteins are important regulatory molecules ubiquitiously expressed in all eukarryotic cells which bind to numerous signaling proteins in various pathways driving critical cellular pathways of apoptosis, differentiation and cell cycle. 14-3-3 theta specifically has also been shown to play an important regulatory role in the TLR2 signaling pathways as a negative regulator of TLR2 ligand Pam3CySk4 induced NF-kB activation. 14-3-3 theta has previously been shown to interact with TLR4 ligand and MyD88 dependent phosphorylated PkC epsilon. 14-3-3 theta in the TLR4 signaling pathway is a positive regulator controlling release of IRF3 indcuded pro-inflammatory cytokines RANTES and IP-10.
Images
Western blot analysis of 14-3-3 τ (GB111166) at dilution of 1: 500
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.