Артикул
GB111023
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Anti -14-3-3 zeta Rabbit pAb
- Описание
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Product Information
Description
14-3-3 zeta rabbit polyclonal
Protein full name
14-3-3 protein zeta/delta
Synonyms
Protein kinase C inhibitor protein 1, KCIP-1, SEZ-2,Ywhaz, 14-3-3 Delta, 14-3-3 Zeta
Immunogen
Recombinant protein corresponding to
Mouse 14-3-3 zeta
Isotype
IgG
Purity
Affinity purification
Subcellular location
Predicted MW.
28 kDa
Observed MW.
28 kDa
Uniprot ID
Applications
Applications
Species
Dilution
Positive Tissue
WB
Human, Mouse, Rat
1: 500-1: 1000
lung, kidney, brain
IHC
Mouse, Rat
1: 1000-1: 2000
brain
IF
Mouse, Rat
1: 500-1: 1000
brain
Background
YWHAZ belongs to the 14-3-3 family of proteins which are in charge for checkpoint control, apoptotic & nutrient sensing pathways as well as signal transduction by binding to phosphoserine-containing proteins. This highly conserved and ubiquitously expressed protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. It interacts with IRS1 protein,signifying a role in regulating insulin. YWHAZ function as an adapter protein involved in the regulation of a large spectrum of both general and specialized signaling pathway. YWHAZ binds to a large number of partners,usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
Images
Western blot analysis of 14-3-3 zeta (GB111023) at dilution of 1: 1000
Lane 1: Hela cell lysate
Lane 2: HepG2 cell lysate
Lane 3: SH-SY5Y cell lysate
Lane 4: Mouse lung tissue lysate
Lane 5: Mouse kidney tissue lysate
Lane 6: Mouse brain tissue lysate
Lane 7: Rat lung tissue lysate
Lane 8: Rat kidney tissue lysate
Lane 9: Rat brain tissue lysate
Immunohistochemistry analysis of paraffin-embedded mouse brain using 14-3-3 zeta (GB111023) at dilution of 1: 2000
Immunohistochemistry analysis of paraffin-embedded rat brain using 14-3-3 zeta (GB111023) at dilution of 1: 2000
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.