быстрая доставка ~4 недели
Размер
- 10 μg
- 1000 μg
- 50 μg
- 500 μg
Recombinant Human IL-13RA1/CD213a1 Protein (RP00764)
- Описание
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Overview
Product name Recombinant Human IL-13RA1/CD213a1 Protein Catalog No. RP00764 Description Recombinant Human IL-13RA1/IL-13 R alpha 1 Protein is produced by Human cells expression system. The target protein is expressed with sequence (Gly22-Thr343) of human IL-13RA1/IL-13 R alpha 1 (Accession #P78552) fused with a 6×His tag at the C-terminus. Purity > 95% by SDS-PAGE. Endotoxin < 1 EU/μg of the protein by LAL method. Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation. Species Human Background
Interleukin-13 receptor subunit alpha-1(IL13RA1) is a subunit of the interleukin 13 receptor. This subunit formsa receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. The human IL13-R α1was originally cloned based on sequence homology to the mouse IL13-Rα1, it share 76% aa sequence identity.Human The IL13-R α 1 cDNA encodes a 427 amino acid (aa) residue precursor protein with a putative 21 aaresidue signal peptide, a 324 aa residue extracellular domain, a 23 aa residue transmembrane region and a 59aa residue cytoplasmic tail. The extracellular domain of IL13-Rα 1 is also closely related to that of IL13-Rα 2. Itbinds with low affinity to interleukin-13(IL13). IL13RA1 serves as a primary IL13- binding subunit of the IL13receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinaseTYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6induced by IL13 and IL4.Product information
Synonym Interleukin-13 receptor subunit alpha-1; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; Cancer/testis antigen 19; CT19; CD213a1; IL13RA1; IL13R; IL13RA Expression Host HEK293 cells Tag C-His Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. * For research use only. Not for therapeutic or diagnostic purposes.
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