быстрая доставка ~4 недели
Размер
- 10 μg
- 1000 μg
- 50 μg
- 500 μg
Recombinant Human KP43/CD94 Protein (RP00567)
- Описание
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Overview
Product name Recombinant Human KP43/CD94 Protein Catalog No. RP00567 Description Recombinant Human CD94/Natural Killer Cells Antigen CD94 Protein is produced by Human cells expression system. The target protein is expressed with sequence (Ser34-Ile179) of human CD94/Natural Killer Cells Antigen CD94 (Accession #Q13241) fused with a 6×His tag at the N-terminus. Purity > 95% by SDS-PAGE. Endotoxin < 1 EU/μg of the protein by LAL method. Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation. Species Human Background
CD94 (Cluster of Differentiation 94), also known as killer cell lectin-like receptor subfamily D member 1(KLRD1), is expressed on the surface of natural killer cells in the innate immune system. CD94 Plays a role as areceptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. CD94 Canform disulfide-bonded heterodimer with NKG2 family members. The CD94/NKG2 complex, on the surface ofnatural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells. Natural killer (NK) cells are adistinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immunestimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, areexpressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigenpreferentially expressed on NK cells and is classified as a type II membrane protein because it has an external Cterminus.Product information
Synonym Natural killer cells antigen CD94; KP43; Killer cell lectin-like receptor subfamily D member 1; NKcell receptor; CD94; KLRD1 Expression Host HEK293 cells Tag N-His Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. * For research use only. Not for therapeutic or diagnostic purposes.
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