быстрая доставка ~4 недели
Размер
- 100 μg
- 20 μg
- 200 μg
- 50 μg
Active Recombinant Human TNFRSF10B/DR5/TRAIL-R2 Protein (RP00282)
- Описание
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Overview
Product name Active Recombinant Human TNFRSF10B/DR5/TRAIL-R2 Protein Catalog No. RP00282 Description Active Recombinant Human TNFRSF10B/DR5/TRAIL-R2 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ile 56 - Glu 182) of human DR5 (Accession #NP_003833.3) fused with a 6×His tag at the C-terminus. Bio-Activity Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human TRAIL at 2 μg/mL (100 μL/well) can bind Recombinant Human DR5 with a linear range of 14-56 ng/mL. Purity > 90% by SDS-PAGE. Endotoxin < 0.1 EU/μg of the protein by LAL method. Formulation Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation. Species Human Background
This protein is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.Product information
Synonym CD262 Protein; Human; DR5 Protein; Human; KILLER Protein; Human; KILLER/DR5 Protein; Human; TRAIL-R2 Protein; Human; TRAILR2 Protein; Human; TRICK2 Protein; Human; TRICK2A Protein; Human; TRICK2B Protein; Human; TRICKB Protein; Human; ZTNFR9 Protein; Human Expression Host HEK293 cells Tag C-His Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. * For research use only. Not for therapeutic or diagnostic purposes.
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