быстрая доставка ~4 недели
Размер
- 10 μg
- 100 μg
- 50 μg
Recombinant Human IL-5RA/CD125 Protein (RP02235)
- Описание
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Overview
Product name Recombinant Human IL-5RA/CD125 Protein Catalog No. RP02235 Description Recombinant Human IL-5RA/CD125 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (IL5RA(Asp21-Pro338)) of human IL5RA (Accession #) fused with a His tag at the C-terminus. Purity > 90% by SDS-PAGE. Formulation Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 68 % trehalose is added as protectants before lyophilization. Species Human Background
The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.Product information
Synonym IL5Ra; CD125; IL-5 R alpha Expression Host HEK293 cells Tag C-His Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80°C for long term.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.Reconstitution Reconstitute with deionized water * For research use only. Not for therapeutic or diagnostic purposes.
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