быстрая доставка ~4 недели
Размер
- 10 μg
- 100 μg
- 50 μg
Recombinant Human IL-3RA/CD123 Protein (RP02233)
- Описание
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Overview
Product name Recombinant Human IL-3RA/CD123 Protein Catalog No. RP02233 Description Recombinant Human IL-3RA/CD123 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (CD123(Thr19-Arg305)&hFc(Glu99-Ala330)) of human IL3RA (Accession #) fused with a Fc and His Tag at the C-terminal. . Bio-Activity ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human CD123, hFc-His tagged protein can bind Anti-CD123 Neutralizing antibody in a linear range of 0.98-26.70 ng/ml. Purity > 95% by SDS-PAGE. Formulation Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 10 % trehalose is added as protectants before lyophilization. Species Human Background
Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cellsProduct information
Synonym IL3R; IL3RA; IL-3Ra; IL-3R-alpha; IL3RAY; IL3RX; IL3RY; CD123 antigen; CD123; hIL3Ra; hIL-3Ra; MGC34174; IL-3 R alpha Expression Host HEK293 cells Tag C-hFc&His Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80°C for long term.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.Reconstitution Reconstitute with deionized water * For research use only. Not for therapeutic or diagnostic purposes.
Product Protocols