быстрая доставка ~4 недели
Размер
- 10 μg
- 1000 μg
- 50 μg
- 500 μg
Recombinant Mouse B7-H3/CD276 Protein (RP00717)
- Описание
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Overview
Product name Recombinant Mouse B7-H3/CD276 Protein Catalog No. RP00717 Description Recombinant Mouse B7-H3/CD276 Protein is produced by Human Cells expression system. The target protein is expressed with sequence (Val29-Phe244) of mouse B7-H3/CD276 (Accession #Q8VE98) fused with a 6×His tag at the C-terminus. Purity > 95% by SDS-PAGE. Endotoxin < 1 EU/μg of the protein by LAL method. Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation. Species Mouse Background
CD276, also known as B7-H3, is a member of the B7 superfamily with signature IgV and IgG regions inextracellular domains. It is a type I transmembrane protein and shares 20–27% amino acid identity with otherB7 family members. B7-H3 is involved in the activation of T lymphocytes, and regulates murine boneformation. It is also reported that B7-H3 may play an important role in muscle-immune interactions, providingfurther evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is expressed onT-cells, natural killer cells, and antigen presenting cells, as well as some non-immune cells, such as osteoblasts, fibroblasts, fibroblast-like synoviocytes and epithelial cells. High expression of B7-H3 in tumor vasculature alsocorrelates with poor survival in patients, suggesting that it may play a role in tumor cell migration.Product information
Synonym CD276 antigen; CD276; B7 homolog 3; B7-H3; CD276 Expression Host HEK293 cells Tag C-His Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. * For research use only. Not for therapeutic or diagnostic purposes.
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