быстрая доставка ~4 недели
Размер
- 100 μg
- 50 μg
Recombinant Human Insulin Receptor/INSR/CD220 Protein (RP01146)
- Описание
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Overview
Product name Recombinant Human Insulin Receptor/INSR/CD220 Protein Catalog No. RP01146 Description Recombinant Human Insulin Receptor/INSR/CD220 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Lys956) of human Insulin Receptor (Accession #NP_000199.2) fused with a 6×His tag at the C-terminus. Purity > 95 % by SDS-PAGE. Endotoxin < 1.0 EU/μg of the protein by LAL method. Formulation Lyophilized from a 0.22 μm filtered solution PBS, pH 7.4.Contact us for customized product form or formulation. Species Human Background
This protein is a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.Product information
Synonym CD220; HHF5; Insulin Receptor; Insulin Receptor Expression Host HEK293 cells Tag C-His Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. * For research use only. Not for therapeutic or diagnostic purposes.
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