быстрая доставка ~4 недели
Размер
- 100 μg
- 50 μg
Recombinant Human TNFRSF4/OX40/CD134 Protein (RP01127)
- Описание
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Overview
Product name Recombinant Human TNFRSF4/OX40/CD134 Protein Catalog No. RP01127 Description Recombinant Human TNFRSF4/OX40/CD134 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Ala216) of human OX40 (Accession #NP_003318.1) fused with a 6×His tag at the C-terminus. Bio-Activity Measured by its binding ability in a functional ELISA. Immobilized Human TNFRSF4 at 2 μg/mL (100 μL/well) can bind Human TNFSF4, the EC50 is 60-240 ng/mL. Purity > 90 % by SDS-PAGE. Endotoxin < 1.0 EU/μg of the protein by LAL method. Formulation Lyophilized from a 0.22 μm filtered solution PBS, pH 7.4.Contact us for customized product form or formulation. Species Human Background
This protein is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.Product information
Synonym ACT35; CD134; IMD16; OX40; TXGP1L; OX40 Expression Host HEK293 cells Tag C-His Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. * For research use only. Not for therapeutic or diagnostic purposes.
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