быстрая доставка ~4 недели
Размер
- 100 μg
- 1000 μg
- 500 μg
Recombinant Human CD47 Protein (RP02027)
- Описание
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Overview
Product name Recombinant Human CD47 Protein Catalog No. RP02027 Description Recombinant Mouse B7-H5 Protein is produced by mammalian expression system. The target protein is expressed with sequence (Gln19-Pro139) of human CD47 (Accession #Q08722) fused with a 6xHis tag at the C-terminus. Bio-Activity Immobilized Human CD47 at 0.5 μg/mL (100 μL/well), dose response curve for Human SIRP alpha with the EC50 of 96.15 ng/mL determined by ELISA. Purity > 95% by SDS-PAGE. Endotoxin < 0.1 EU/μg of the protein by LAL method. Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation. Species Human Background
CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα).CD-47 acts as a don't eat me signal to macrophages of the immune system which has made it a potential therapeutic target in some cancers.Product information
Synonym IAP; MER6; OA3 Expression Host HEK293 cells Tag C-His Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. * For research use only. Not for therapeutic or diagnostic purposes.
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