быстрая доставка ~4 недели
Размер
- 10 μg
- 1000 μg
- 50 μg
- 500 μg
Recombinant Mouse IL-12B&IL-23A Protein (RP00763)
- Описание
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Overview
Product name Recombinant Mouse IL-12B&IL-23A Protein Catalog No. RP00763 Description Recombinant Mouse IL-23 (IL-23A&IL-12B) Protein is produced by Human Cells expression system. The target protein is expressed with sequence (Val22-Ala196&Met23-Ser335) of mouse IL-23 (IL-23A&IL-12B) (Accession #Q9EQ14&P43432). Purity > 95% by SDS-PAGE. Endotoxin < 1 EU/μg of the protein by LAL method. Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation. Species Mouse Background
Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit thatis unique to IL-23, and a p40 subunit that is shared with IL-12. The p19 subunit has homology to the p35subunit of IL-12, as well as to other single chain cytokines such as IL-6 and IL-11. The p40 subunit is homologousto the extracellular domains of the hematopoietic cytokine receptors. Although p19 is expressed by activatedmacrophages, dendritic cells, T cells, and endothelial cells, only activated macrophages and dendritic cellsexpress p40 concurrently to produce IL-23. IL-23 has biological activities that are similar to, but distinct from IL-12. Both IL-12 and IL-23 induce proliferation and IFN-gamma production by human T cells. While IL-12 acts onboth naive and memory human T cells, the effects of IL-23 is restricted to memory T cells.Product information
Synonym SGRF; IL-23p19; CLMF p40; IL-12 subunit p40; NKSF2 Expression Host HEK293 cells Tag No tag Swiss-Prot Usage guide
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. * For research use only. Not for therapeutic or diagnostic purposes.
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