быстрая доставка ~4 недели
Размер
- 10 μg
- 1000 μg
- 50 μg
- 500 μg
Recombinant Mouse IL-23R Protein (RP00689)
- Описание
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Overview
Product name Recombinant Mouse IL-23R Protein Catalog No. RP00689 Description Recombinant Mouse IL-23R/IL-23 Receptor Protein is produced by Human Cells expression system. The target protein is expressed with sequence (Gly24-Asp372) of mouse IL-23R/IL-23 Receptor (Accession #Q8K4B4) fused with an Fc tag at the C-terminus. Purity > 95% by SDS-PAGE. Endotoxin < 1 EU/μg of the protein by LAL method. Formulation Lyophilized from a 0.2 μM filtered solution of PBS, pH 7.4Contact us for customized product form or formulation. Species Mouse Background
Interleukin 23 receptor (IL23R), a heterodimer of the IL12 receptor β 1 (IL12R β 1) and IL12R β 2, is a type Icytokine receptor for IL23. IL23R is comprised of two subunits, the IL12R β 1 subunit, which is shared withseveral cytokines, and a subunit that is unique to IL-23. IL23, after binding to IL23R, activates memory T cellsand mediates pro-inflammatory activities in part by the production of IL17 through activation of TH17lymphocytes. IL23R is expressed on T cells, NK cells, dendritic cells, and macrophages. In fact, polymorphismsof the IL23R gene were reported to be associated with susceptibility to inflammatory diseases andautoimmune diseases such as psoriasis, multiple sclerosis, Graves's ophtalmopathy and inflammatory boweldiseases. The IL23R is known to be critically involved in the carcinogenesis of different malignant tumor.Product information
Synonym Interleukin-23 receptor; Il23r; IL-23 receptor; IL-23R; interleukin 23 receptor Expression Host HEK293 cells Tag C-Fc Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. * For research use only. Not for therapeutic or diagnostic purposes.
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