быстрая доставка ~4 недели
Размер
- 10 μg
- 1000 μg
- 50 μg
- 500 μg
Recombinant Mouse TNFRSF4/OX40/CD134 Protein (RP00676)
- Описание
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Overview
Product name Recombinant Mouse TNFRSF4/OX40/CD134 Protein Catalog No. RP00676 Description Recombinant Mouse TNFRSF4/OX40 Protein is produced by Human Cells expression system. The target protein is expressed with sequence (Val20-Pro211) of mouse TNFRSF4/OX40 (Accession #P47741) fused with an Fc tag at the C-terminus. Purity > 95% by SDS-PAGE. Endotoxin < 1 EU/μg of the protein by LAL method. Formulation Lyophilized from a 0.2 μM filtered solution of PBS, pH 7.4Contact us for customized product form or formulation. Species Mouse Background
OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamilywhich plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed onCD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation byCD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand (OX40L) will occur whenactivated T cells bind to professional antigen-presenting cells (APCs). The T-cell functions, including cytokineproduction, expansion, and survival, are then enhanced by the OX40 costimulatory signals. OX40 signals arecritical for controlling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40L interactionregulates T-cell tolerance, peripheral T-cell homeostasis, and T-cell-mediated inflammatory diseases.Product information
Synonym Tumor necrosis factor receptor superfamily member 4; Tnfrsf4; OX40; CD134; Txgp1 Expression Host HEK293 cells Tag C-Fc Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in 1X PBS. * For research use only. Not for therapeutic or diagnostic purposes.
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