быстрая доставка ~4 недели
Размер
- 100 μg
- 20 μg
- 50 μg
- Описание
-
Overview
Product name Recombinant Human BMP-2 Protein Catalog No. RP02510 Description Recombinant Human BMP-2 Protein is produced by Escherichia coli expression system. The target protein is expressed with sequence of Human BMP-2 fused with polyhistidine tag at the C-terminus Bio-Activity Measured by its ability to inhibit alkaline phosphatase production by ATDC5 cells. The ED50 for this effect is <9.5 ng/mL. The specific activity of recombinant BMP-2 is > 3.2 x 106 IU/mg. Purity > 95% by SDS-PAGE. Endotoxin <0.1EU/ug Formulation Lyophilized from a 0.22 μm filtered solution of 20 mM sodium citrate, 0.2 M NaCl, pH 3.5. Species Human Background
BMP-2 like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. It is involved in the hedgehog pathway, TGF beta signaling pathway, and in cytokine-cytokine receptor interaction. It is also involved in cardiac cell differentiation and epithelial to mesenchymal transition. Like many other proteins from the BMP family, BMP-2 has been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2 may be involved in white adipogenesis and may have metabolic effectsProduct information
Synonym Bone Morphogenetic Protein 2; BMP-2; Bone Morphogenetic Protein 2A; BMP-2A; BMP2; BMP2A Expression Host E. coli Tag C-His Swiss-Prot Gene ID Usage guide
Storage Store the lyophilized protein at -20°C to -80°C for long term.
After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. * For research use only. Not for therapeutic or diagnostic purposes.
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