![[KO Validated] TDP2 Rabbit pAb (A18017)](/upload/resize_cache/iblock/7b6/340_340_140cd750bba9870f18aada2478b24840a/nmrw67hnl5zseo5oalc2zd1s8d75dgvr.jpg "[KO Validated] TDP2 Rabbit pAb (A18017)")
быстрая доставка ~4 недели
Размер
- 100 μL
- 200 μL
- 50 μL
[KO Validated] TDP2 Rabbit pAb (A18017)
- Описание
- Характеристики
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Overview
Product name [KO Validated] TDP2 Rabbit pAb Catalog No. A18017 Host species Rabbit Purification method Affinity purification Isotype IgG Background
This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.Immunogen information
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human TDP2 (NP_057698.2). Sequence MELGSCLEGGREAAEEEGEPEVKKRRLLCVEFASVASCDAAVAQCFLAENDWEMERALNSYFEPPVEESALERRPETISEPKTYVDLTNEETTDSTTSKISPSEDTQQENGSMFSLITWNIDGLDLNNLSERARGVCSYLALYSPDVIFLQEVIPPYYSYLKKRSSNYEIITGHEEGYFTAIMLKKSRVKLKSQEIIPFP Gene ID Swiss Prot Synonyms EAP2; AD022; EAPII; TTRAP; hTDP2; dJ30M3.3 Calculated MW 41kDa Observed MW 41kDa Applications
Reactivity Human, Mouse Tested applications WB Recommended dilution - WB 1:500 - 1:2000
Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.Key application Western blotting Positive samples HeLa Cellular location Cytoplasm, Nucleus, PML body, nucleolus 
Western blot analysis of extracts from normal (control) and TDP2 knockout (KO) HeLa cells, using TDP2 antibody (A18017) at 1:3000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 10s. -
Key applications Western blotting Host species Кролик Antibody type Primary Antibodies Reactivity Человек, Мышь Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human TDP2 (NP_057698.2). KO Validated Validated Isotype IgG