быстрая доставка ~4 недели
Размер
- 100 T
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- 500 T
ABflo® 488 Rabbit anti-Human CLEC12A/CD371 mAb (A23105)
- Описание
- Характеристики
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Overview
Product name ABflo® 488 Rabbit anti-Human CLEC12A/CD371 mAb Catalog No. A23105 Host species Rabbit Purification method Affinity purification Isotype IgG CloneNo. ARC55557-ABf488 Background
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13.Immunogen information
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 65-265 of human CLEC12A/CD371 (NP_612210.4). Sequence HVTLKIEMKKMNKLQNISEELQRNISLQLMSNMNISNKIRNLSTTLQTIATKLCRELYSKEQEHKCKPCPRRWIWHKDSCYFLSDDVQTWQESKMACAAQNASLLKINNKNALEFIKSQSRSYDYWLGLSPEEDSTRGMRVDNIINSSAWVIRNAPDLNNMYCGYINRLYVQYYHCTYKKRMICEKMANPVQLGSTYFREA Gene ID Swiss Prot Synonyms CLL1; MICL; CD371; CLL-1; DCAL-2 Calculated MW 8kDa/24kDa/27kDa/30kDa/32kDa Observed MW Applications
Reactivity Human Tested applications FC Recommended dilution - FC 5 μl per 10^6 cells in 100 μl volume
Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.03% proclin300, 0.2% BSA, 50% glycerol, pH7.3.Key application Flow Cytometry Positive samples Cellular location Plasma membrane, specific granule membrane, tertiary granule membrane 
Flow cytometry:1X10^6 K-562 cells (negative control, Left) and U-937 cells (Right) were surface-stained with ABflo® 488 Rabbit anti-Human CLEC12A/CD371 mAb(A23105, 5 μl/Test, orange line) or ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, blue line). Non-fluorescently stained cells was used as blank control (red line).
Flow cytometry:1X10^6 U-937 cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, left) or ABflo® 488 Rabbit anti-Human CLEC12A/CD371 mAb(A23105, 5 μl/Test, right).
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Key applications Flow Cytometry Host species Кролик Antibody type Primary Antibodies Reactivity Человек Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 65-265 of human CLEC12A/CD371 (NP_612210.4). Isotype IgG