быстрая доставка ~4 недели
Размер
- 100 T
- 200 T
- 500 T
ABflo® 488 Rabbit anti-Mouse CD271/NGFR mAb (A24321)
- Описание
- Характеристики
-
Overview
Product name ABflo® 488 Rabbit anti-Mouse CD271/NGFR mAb Catalog No. A24321 Host species Rabbit Purification method Affinity purification Isotype IgG CloneNo. ARC62149-ABflo488 Background
Enables death receptor activity; nerve growth factor binding activity; and small GTPase binding activity. Involved in several processes, including cellular glucose homeostasis; circadian regulation of gene expression; and dorsal aorta development. Acts upstream of or within several processes, including hair follicle morphogenesis; nervous system development; and regulation of signal transduction. Located in several cellular components, including cell surface; cell-cell junction; and postsynaptic density. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease and mental depression. Orthologous to human NGFR (nerve growth factor receptor).Immunogen information
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 32-254 of mouse CD271 (NP_150086.2) . Sequence KETCSTGMYTHSGECCKACNLGEGVAQPCGANQTVCEPCLDSVTFSDVVSATEPCKPCTECLGLQSMSAPCVEADDAVCRCSYGYYQDEETGRCEACSVCGVGSGLVFSCQDKQNTVCEECPEGTYSDEANHVDPCLPCTVCEDTERQLRECTPWADAECEEIPGRWITRSTPPEGSDVTTPSTQEPEAPPERDLIASTVADTVTTVMGSSQPVVTRGTADNL Gene ID Swiss Prot Synonyms p75; LNGFR; p75NTR; p75NGFR; Tnfrsf16 Calculated MW 45kDa Observed MW Refer to figures Applications
Reactivity Mouse Tested applications FC Recommended dilution - FC 5 μl per 10^6 cells in 100 μl volume
Storage buffer Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.03% proclin300, 0.2% BSA, 50% glycerol, pH7.3.Key application Flow Cytometry Positive samples Cellular location Cell membrane, Single-pass type I membrane protein, Curated Perikaryon, Cell projection, growth cone, Cell projection, dendritic spine 
Flow cytometry:1X10^6 293F cells (negative control, Left) and 293F(Transfection) cells (Right) were surface-stained with ABflo® 488 Rabbit anti-Mouse CD271/NGFR mAb(A24321, 5 μl/Test, orange line) or ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, blue line). Non-fluorescently stained cells were used as blank control (red line).
Flow cytometry:1X10^6 293F(Transfection) cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, left) or ABflo® 488 Rabbit anti-Mouse CD271/NGFR mAb(A24321, 5 μl/Test, right)
-
Key applications Flow Cytometry Host species Кролик Antibody type Primary Antibodies Reactivity Мышь Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 32-254 of mouse CD271 (NP_150086.2) . Isotype IgG