- Описание
-
Product Information
Description
ACSS2 rabbit polyclonal
Protein full name
Acetyl-coenzyme A synthetase, cytoplasmic
Synonyms
AceCS,ACSS2, ACAS2, Acyl-activating enzyme, Acetate--CoA ligase, Acetyl-CoA synthetase,
ACS, Acyl-CoA synthetase short-chain family member 2, ACSA
Immunogen
Recombinant protein corresponding to Mouse ACSS2
Isotype
IgG
Purity
Affinity purification
Subcellular location
Uniprot ID
Applications
Applications
Species
Dilution
Positive Tissue
IHC
Human
1: 500-1: 1000
kidney, liver
IF
Human
1: 250-1: 500
kidney, liver
Background
ACSS2 (acyl-CoA synthetase short-chain family member 2), also known as ACAS2, ACS, ACSA or AceCS, is a 701 amino acid cytoplasmic protein that belongs to the ATP-dependent AMP-binding enzyme family. Existing as a monomer, ACSS2 functions to catalyze the ATP-dependent activation of acetate, a reaction that yields acetyl-CoA for use in energy generation and lipid synthesis. ACSS2 expression, which is highest in liver and kidney tissue, is regulated by the presence of unsaturated fatty acids and sterol regulatory element-binding proteins (SREBPs). Human ACSS2 exists as two alternatively spliced isoforms and shares 93% sequence identity with its mouse counterpart, suggesting a conserved role between species.
Images

Immunohistochemistry analysis of paraffin-embedded human lung cancer using ACSS2 (GB11967) at dilution of 1: 500

Immunohistochemistry analysis of paraffin-embedded human ovarian cancer using ACSS2 (GB11967) at dilution of 1: 500

Immunohistochemistry analysis of paraffin-embedded human stomach using ACSS2 (GB11967) at dilution of 1: 500
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).










