Артикул
GB113859
быстрая доставка ~4 недели
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Anti -AFG3L2 Rabbit pAb
- Описание
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Product Information
Description
AFG3L2rabbit polyclonalantibody
Protein full name
AFG3-like protein 2
Synonyms
AFG3 like protein 2, AFG3L2, Paraplegin like protein, SCA28, Spinocerebellar ataxia 28, AFG3 ATPase family gene 3 like 2
Immunogen
KLH conjugated Synthetic peptide
corresponding to Mouse AFG3L2
Isotype
IgG
Purity
Affinity purification
Predicted MW.
90 kDa
Observed MW.
90kDa
Uniprot ID
Applications
Applications
Species
Dilution
Positive Sample
WB
Human, Mouse, Rat
1:1000-1:2000
liver, brain, kidney
Background
AFG3L2 is the catalytic subunit of the m-AAA protease, an ATP-dependent proteolytic complex of the mitochondrial inner membrane that degrades misfolded proteins and regulates ribosome assembly. Human AFG3L2 is an 80-kDa protein encoded by a 17-exon gene and highly and selectively expressed in human cerebellar Purkinje cells and it can exsit as a truncated 65 kDa protein. Defects in AFG3L2 are the cause of spinocerebellar ataxia type 28 (SCA28) and spastic ataxia autosomal recessive type 5 (SPAX5).
Images
Western blot analysis of AFG3L2 (GB113859) at dilution of 1: 2000 Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.