Артикул
GB111263
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Anti -ADRM1/ARM-1 Rabbit pAb
- Описание
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Product Information
Description
ADRM1 rabbit polyclonal antibody
Protein full name
Proteasomal ubiquitin receptor ADRM1
Synonyms
110 kDa cell membrane glycoprotein, Gp110, Adhesion-regulating molecule 1, ARM-1, Rpn13 homolog, ADRM1, Gp110
Immunogen
Recombinant protein corresponding to Mouse ADRM1
Isotype
IgG
Purity
Affinity purification
Subcellular location
Cytoplasm,Nucleus
Uniprot ID
Q16186, Q9JMB5
Applications
Applications
Species
Dilution
Positive Sample
IHC/IF
Human, Mouse, Rat
1: 1000-1: 2000
brain, breast cancer, colon cancer, esophagus, lung
Background
ADRM1 is a 407 amino acid protein that localizes to both the nucleus and the cytoplasm and is thought to be involved in protein recruitment and cell adhesion. An integral membrane protein, ADRM1 functions to recruit UCH-L5, a deubiquitinating enzyme, to the 26S proteasome, and once at the proteasome it promotes the activity of UCH-L5. Additionally, ADRM1 is thought to mediate lymphocyte adhesion in endothelial cells and may thus play a role in lymphocyte homing. ADRM1 expression is induced by IFN-g in some cancer cell lines and its expression is upregulated in other metastatic cells, suggesting a role in carcinogenesis.
Images
Immunohistochemistry of paraffin embedded human breast cancer using ADRM1 (GB111263) at dilution of 1:1000 (400x lens) 
Immunohistochemistry of paraffin embedded human colon cancer using ADRM1 (GB111263) at dilution of 1:1000 (400x lens) 
Immunohistochemistry of paraffin embedded human esophagus using ADRM1 (GB111263) at dilution of 1:1000 (400x lens) 
Immunohistochemistry of paraffin embedded mouse brain using ADRM1 (GB111263) at dilution of 1:1000 (400x lens) 
Immunohistochemistry of paraffin embedded mouse lung using ADRM1 (GB111263) at dilution of 1:1000 (400x lens) 
Immunohistochemistry of paraffin embedded rat brain using ADRM1 (GB111263) at dilution of 1:1000 (400x lens) 
Immunohistochemistry of paraffin embedded rat lung using ADRM1 (GB111263) at dilution of 1:1000 (400x lens) Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.