Артикул
GB111002
быстрая доставка ~4 недели
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Anti -5HT2C Receptor Rabbit pAb
- Описание
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Product Information
Description
5HT2C Receptor rabbit polyclonal antibody
Protein full name
5-hydroxytryptamine receptor 2C
Synonyms
5-ht-1c receptor, 5HT1C, 5HT2C, 5HTR2C, G protein-coupled, 5-hydroxytryptamine receptor 1C, 5-hydroxytryptamine receptor 2C, Htr1c, HTR2C, serotonin 1c receptor, serotonin 2c receptor, Serotonin 5-HT-2C receptor
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse 5HT2C Receptor
Isotype
IgG
Purity
Affinity purification
Predicted MW.
52 kDa
Observed MW.
52 kDa
Uniprot ID
P34968, P08909
Applications
Applications
Species
Dilution
Positive Tissue
WB
Mouse, Rat
1: 500-1: 1000
brain, cerebral cortex , cerebellum, hippocampus
Background
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.5HT2C is a 45 kDa 7TM receptor for serotonin and is neuronally expressed in the limbic system of the brain. The release of dopamine due to 5HT2C ligation regulates mood, appetite, and motivation. 5HT2C is an important pharmacologic target in the treatment of psychosis, schizophrenia, depression, anxiety and migrane headaches. Multiple isoforms of 5HT2C can be generated by RNA editing. Human 5HT2C shares 89% aa sequence identity with mouse and rat 5HT2C.
Images
Western blot analysis of 5-HT2C (GB111002) at dilution of 1: 500
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.