Артикул
GB11018
быстрая доставка ~4 недели
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Anti -JNK1+JNK2+JNK3 Rabbit pAb
- Описание
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Product Information
Description JNK1+JNK2+JNK3 rabbit polyclonalantibody
Protein full name Mitogen-activated protein kinase 8/9/10 Synonyms JNK1 + JNK2 + JNK3,JNK1/2/3,JNK1+2+3,MAPK8, MAPK9,MAPK10,c Jun N terminal kinase 1,c Jun N terminal kinase 2,c Jun N terminal kinase 3
Immunogen KLH conjugated Synthetic peptide corresponding to human JNK1
Isotype IgG Purity Affinity purification Subcellular location
Cytoplasm, Nucleus Uniprot ID P45983,P45984,P53779 Applications
Applications
Species
Dilution
Positive Sample
IHC/IF
Mouse, Rat
1: 200-1: 800
brain, lung
Background
JNK1(MAPK8) is a member of the MAP kinase family. JNK1 is activated by threonine and tyrosine phosphorylation by either of two dual specificity kinases, MAP2K4 and MAP2K7.
JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.
JNK3 is a neuron-specific form of c-Jun N-terminal kinases. Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways of neuronal apoptosis.
Images
Immunohistochemistry of paraffin embedded mouse brain using JNK123 (GB11018) at dilution of 1:400 (400x lens)
Immunohistochemistry of paraffin embedded mouse lung using JNK123 (GB11018) at dilution of 1:400 (400x lens)
Immunohistochemistry of paraffin embedded rat brain using JNK123 (GB11018) at dilution of 1:400 (400x lens) 
Immunohistochemistry of paraffin embedded rat lung using JNK123 (GB11018) at dilution of 1:400 (400x lens)
Storage
Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.